List of Articles Reviewed

Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize.
Reviewed June 19th, 2013
Summary: Fail

Monsanto Comments: Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize.
Reviewed June 26th, 2013
Summary: No discovery/finding, but a solid rebuttal to Seralini et al (2012) paper 

The Institute for Responsible Technology (
Reviewed July 3rd, July 8th, July 12th, August 11th, August 24th, November 3rd, November 10th, 2013
Summary: Misleading and often incorrect about health impacts.

Public health implications of the microbial pesticide Bacillus thuringiensis: an epidemiological study, Oregon 1985-86
Reviewed July 8th, 2013
Summary: Has nothing to do with GMO

Characterization of the mucosal and systemic immune response induced by Cry1Ac protein from Bacillus thuringiensis HD 73 in mice.
Reviewed July 12th, 2013
Summary: Did not examine GMOs

Immunological and Metabolomic Impacts of Administration of Cry1Ab Protein and MON 810 Maize in Mouse
Reviewed July 12th, 2013
Summary: Did not find a difference in results between GM and non-GM corn

Poor Gut Health And Autism Linked Through GMOs (from GMO Inside)
Reviewed July 18th, 2013
Summary: No scientific merit. Fail.

Maternal and fetal exposure to pesticides associated to genetically modified foods in Eastern Townships of Quebec, Canada
Reviewed July 27th, 2013
Summary: Interesting finding which need to be reproduced and biological relevance/impact should be determined.

Screening of transgenic proteins expressed in transgenic food crops for the presence of short amino acid sequences identical to potential, IgE – binding linear epitopes of allergens
Reviewed August 11th, 2013
Summary: Used by Anti-GMO (IRT) to highlight the difficulty in determining if GMOs are allergenic. Incorrect use of the article, since it is a computational methods study.

-Reversibility of hepatocyte nuclear modifications in mice fed on genetically modified soybean
-Ultrastructural Morphometrical and Immunocytochemical Analyses of Hepatocyte Nuclei from Mice Fed on Genetically Modified Soybean
Reviewed: August 24th, 2013
Summary: Weak significance for changes in nuclear structures in livers of mice fed GM-soy. Both studies were not designed properly.

Assessment of the health impact of GM plant diets in long-term and multigenerational animal feeding trials: a literature review
Reviewed: September 1st, 2013
Summary: Review of papers that examine long term and multigenerational impact of GM plant diets. Review concludes that long term and multigenerational health impacts have not been identified (and 90 day feeding trials may be sufficient). Review stresses the importance of well-designed studies.

Assessing the survival of transgenic plant DNA in the human gastrointestinal tract
Reviewed: November 4th, 2013
Summary: Used by Anti-GMO advocates to highlight the fact that GMO DNA can survive in the gut. The paper shows that DNA is successfully degraded in the gut of healthy individuals, and that GMO and non-GMO DNA behave the same.

Microarray analyses reveal that plant mutagenesis may induce more transcriptomic changes than transgene insertion
Reviewed: November 27th, 2013
Summary: Uses microarray technology (examining gene expression in thousands of genes) to determine if there are unintended consequences of mutagenesis and transgenesis. Paper concludes that both technologies create unintended consequences, but that transgenic plants (i.e. GMOs) have fewer.

Comparison of two GM maize varieties with a near-isogenic non-GM variety using transcriptomics, proteomics and metabolomics
Reviewed: November 27th, 2013
Summary: Paper determines that the environment plays a bigger role in gene expression than whether or not a plant is a GMO

Glyphosate Commercial Formulation Causes Cytotoxicity, Oxidative Effects, and Apoptosis on Human Cells Differences With its Active Ingredient
Reviewed: February 10th, 2014
Summary: Paper uses in vitro system to demonstrate that glyphosate is toxic. However, cell culture systems should not be used to demonstrate toxicity, so the studies conclusions are not representative of an in vivo system 

Complete Genes May Pass from Food to Human Blood
Reviewed: May 31st, 2014
Summary: Paper describes that whole genes from may possibly be detected in plasma, using DNA sequencing technologies. However, crucial controls (such as contamination controls) are not included.
A Comparison of the Effects of Three GM Corn Varieties on Mammalian HealthReviewed: August 28th, 2014
Summary: Paper compiles findings from several industry feeding studies to determine the impact on animal health. Paper seems to be a fishing expedition, and goes through multiple statistical tests till they find a test that finds statistically significant differences between controls and GM-fed animals. Fail. 

High-Throughput Sequence-Based Analysis of the Intestinal Microbiota of Weanling Pigs Fed Genetically Modified MON810 Maize Expressing Bacillus thuringiensis Cry1Ab (Bt Maize) for 31 Days
Reviewed: November 5th, 2014
Summary: Paper does analysis of microbiome of pigs fed Bt-corn and controls and finds very few differences, concluding that Bt is unlikely to impact the microbiome.

Gamma-Glutamyl Transferase Activity in Kids Born from Goats Fed Genetically Modified Soybean
Reviewed: January 15th, 2015
Summary: Paper is an animal feeding study that claims to find differences in gamma-glutamyl transferase activity between GM-fed goats and controls. Paper was subsequently retracted due to image manipulation.

1 comment:

  1. Response to Complete Genes May Pass from Food to Human Blood found here: Diverse and Widespread Contamination Evident in the Unmapped Depths of High Throughput Sequencing Data


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